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Improving Prediction of Carcinogenicity to Reduce, Refine, and Replace the Use of Experimental Animals

Cancer risk assessment of new pharmaceuticals is crucial to protect public health. However, clinical trials lack the duration needed to clearly detect drug-related tumor emergence, and biomarkers suggestive of increased cancer risk from a drug typically are not measured in clinical trials. Therefore...

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Detalhes bibliográficos
Publicado no:J Am Assoc Lab Anim Sci
Main Authors: Bourcier, Todd, McGovern, Tim, Stavitskaya, Lidiya, Kruhlak, Naomi, Jacobson-Kram, David
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for Laboratory Animal Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4382620/
https://ncbi.nlm.nih.gov/pubmed/25836962
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