Atomic accuracy models from 4.5 Å cryo-electron microscopy data with density-guided iterative local refinement

Direct electron detectors have made it possible to generate electron density maps at near atomic resolution using cryo-electron microscopy single particle reconstructions. Critical current questions include how best to build models into these maps, how high quality a map is required to generate an a...

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Bibliografiske detaljer
Udgivet i:Nat Methods
Main Authors: DiMaio, Frank, Song, Yifan, Li, Xueming, Brunner, Matthias J., Xu, Chunfu, Conticello, Vincent, Egelman, Edward, Marlovits, Thomas, Cheng, Yifan, Baker, David
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4382417/
https://ncbi.nlm.nih.gov/pubmed/25707030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.3286
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