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De novo protein structure determination from near-atomic resolution cryo-EM maps
We present a de novo model building approach that combines predicted backbone conformations with side-chain density-fit to accurately assign sequence into density maps. We show this method yields accurate models for six experimental maps at 3.3–4.8 Å resolution, and produces a nearly complete model...
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| Veröffentlicht in: | Nat Methods |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4435692/ https://ncbi.nlm.nih.gov/pubmed/25707029 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.3287 |
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