Skin barrier dysfunction measured by transepidermal water loss at 2 days and 2 months predates and predicts atopic dermatitis at 1 year

BACKGROUND: Loss-of-function mutations in the skin barrier protein filaggrin (FLG) are a major risk for atopic dermatitis (AD). The pathogenic sequence of disturbances in skin barrier function before or during the early development of AD is not fully understood. A more detailed understanding of thes...

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Detalles Bibliográficos
Publicado en:J Allergy Clin Immunol
Autores principales: Kelleher, Maeve, Dunn-Galvin, Audrey, Hourihane, Jonathan O'B., Murray, Deirdre, Campbell, Linda E., McLean, W.H. Irwin, Irvine, Alan D.
Formato: Artigo
Lenguaje:Inglês
Publicado: Mosby 2015
Materias:
Atopic Dermatitis and Skin Disease
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4382348/
https://ncbi.nlm.nih.gov/pubmed/25618747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2014.12.013
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