Skin barrier dysfunction measured by transepidermal water loss at 2 days and 2 months predates and predicts atopic dermatitis at 1 year

BACKGROUND: Loss-of-function mutations in the skin barrier protein filaggrin (FLG) are a major risk for atopic dermatitis (AD). The pathogenic sequence of disturbances in skin barrier function before or during the early development of AD is not fully understood. A more detailed understanding of thes...

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Библиографические подробности
Опубликовано в: :J Allergy Clin Immunol
Главные авторы: Kelleher, Maeve, Dunn-Galvin, Audrey, Hourihane, Jonathan O'B., Murray, Deirdre, Campbell, Linda E., McLean, W.H. Irwin, Irvine, Alan D.
Формат: Artigo
Язык:Inglês
Опубликовано: Mosby 2015
Предметы:
Atopic Dermatitis and Skin Disease
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4382348/
https://ncbi.nlm.nih.gov/pubmed/25618747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2014.12.013
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