Protein tyrosine phosphatase–σ regulates hematopoietic stem cell–repopulating capacity

Hematopoietic stem cell (HSC) function is regulated by activation of receptor tyrosine kinases (RTKs). Receptor protein tyrosine phosphatases (PTPs) counterbalance RTK signaling; however, the functions of receptor PTPs in HSCs remain incompletely understood. We found that a receptor PTP, PTPσ, was s...

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Detaylı Bibliyografya
Yayımlandı:J Clin Invest
Asıl Yazarlar: Quarmyne, Mamle, Doan, Phuong L., Himburg, Heather A., Yan, Xiao, Nakamura, Mai, Zhao, Liman, Chao, Nelson J., Chute, John P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2014
Konular:
Brief Report
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4382260/
https://ncbi.nlm.nih.gov/pubmed/25415437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI77866
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