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Essential role for autophagy in life span extension

Life and health span can be prolonged by calorie limitation or by pharmacologic agents that mimic the effects of caloric restriction. Both starvation and the genetic inactivation of nutrient signaling converge on the induction of autophagy, a cytoplasmic recycling process that counteracts the age-as...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Clin Invest
Prif Awduron: Madeo, Frank, Zimmermann, Andreas, Maiuri, Maria Chiara, Kroemer, Guido
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Clinical Investigation 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4382258/
https://ncbi.nlm.nih.gov/pubmed/25654554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI73946
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