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Essential role for autophagy in life span extension

Life and health span can be prolonged by calorie limitation or by pharmacologic agents that mimic the effects of caloric restriction. Both starvation and the genetic inactivation of nutrient signaling converge on the induction of autophagy, a cytoplasmic recycling process that counteracts the age-as...

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Bibliografske podrobnosti
izdano v:J Clin Invest
Main Authors: Madeo, Frank, Zimmermann, Andreas, Maiuri, Maria Chiara, Kroemer, Guido
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4382258/
https://ncbi.nlm.nih.gov/pubmed/25654554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI73946
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