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Autophagy mediates pharmacological lifespan extension by spermidine and resveratrol

Although autophagy has widely been conceived as a self-destructive mechanism that causes cell death, accumulating evidence suggests that autophagy usually mediates cytoprotection, thereby avoiding the apoptotic or necrotic demise of stressed cells. Recent evidence produced by our groups demonstrates...

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Bibliografske podrobnosti
Main Authors: Morselli, Eugenia, Galluzzi, Lorenzo, Kepp, Oliver, Criollo, Alfredo, Maiuri, Maria Chiara, Tavernarakis, Nektarios, Madeo, Frank, Kroemer, Guido
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2815753/
https://ncbi.nlm.nih.gov/pubmed/20157579
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