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Autophagy mediates pharmacological lifespan extension by spermidine and resveratrol

Although autophagy has widely been conceived as a self-destructive mechanism that causes cell death, accumulating evidence suggests that autophagy usually mediates cytoprotection, thereby avoiding the apoptotic or necrotic demise of stressed cells. Recent evidence produced by our groups demonstrates...

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Autores principales: Morselli, Eugenia, Galluzzi, Lorenzo, Kepp, Oliver, Criollo, Alfredo, Maiuri, Maria Chiara, Tavernarakis, Nektarios, Madeo, Frank, Kroemer, Guido
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2815753/
https://ncbi.nlm.nih.gov/pubmed/20157579
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