Autophagy mediates pharmacological lifespan extension by spermidine and resveratrol

Although autophagy has widely been conceived as a self-destructive mechanism that causes cell death, accumulating evidence suggests that autophagy usually mediates cytoprotection, thereby avoiding the apoptotic or necrotic demise of stressed cells. Recent evidence produced by our groups demonstrates...

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Bibliografiske detaljer
Main Authors: Morselli, Eugenia, Galluzzi, Lorenzo, Kepp, Oliver, Criollo, Alfredo, Maiuri, Maria Chiara, Tavernarakis, Nektarios, Madeo, Frank, Kroemer, Guido
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2009
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2815753/
https://ncbi.nlm.nih.gov/pubmed/20157579
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