Spermidine and resveratrol induce autophagy by distinct pathways converging on the acetylproteome

Autophagy protects organelles, cells, and organisms against several stress conditions. Induction of autophagy by resveratrol requires the nicotinamide adenine dinucleotide–dependent deacetylase sirtuin 1 (SIRT1). In this paper, we show that the acetylase inhibitor spermidine stimulates autophagy ind...

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Hlavní autoři: Morselli, Eugenia, Mariño, Guillermo, Bennetzen, Martin V., Eisenberg, Tobias, Megalou, Evgenia, Schroeder, Sabrina, Cabrera, Sandra, Bénit, Paule, Rustin, Pierre, Criollo, Alfredo, Kepp, Oliver, Galluzzi, Lorenzo, Shen, Shensi, Malik, Shoaib Ahmad, Maiuri, Maria Chiara, Horio, Yoshiyuki, López-Otín, Carlos, Andersen, Jens S., Tavernarakis, Nektarios, Madeo, Frank, Kroemer, Guido
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2011
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Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044119/
https://ncbi.nlm.nih.gov/pubmed/21339330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201008167
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