Chargement en cours...
Genome-Destabilizing Effects Associated with Top1 Loss or Accumulation of Top1 Cleavage Complexes in Yeast
Topoisomerase 1 (Top1), a Type IB topoisomerase, functions to relieve transcription- and replication-associated torsional stress in DNA. We investigated the effects of Top1 on genome stability in Saccharomyces cerevisiae using two different assays. First, a sectoring assay that detects loss of heter...
Enregistré dans:
| Publié dans: | PLoS Genet |
|---|---|
| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2015
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4382028/ https://ncbi.nlm.nih.gov/pubmed/25830313 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005098 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|