Do Cryopreserved Mesenchymal Stromal Cells Display Impaired Immunomodulatory and Therapeutic Properties?

We have recently reported that therapeutic mesenchymal stromal cells (MSCs) have low engraftment and trigger the instant blood mediated inflammatory reaction (IBMIR) after systemic delivery to patients, resulting in compromised cell function. In order to optimize the product, we compared the immunom...

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Publicado en:Stem Cells
Main Authors: Moll, Guido, Alm, Jessica J., Davies, Lindsay C., von Bahr, Lena, Heldring, Nina, Stenbeck-Funke, Lillemor, Hamad, Osama A., Hinsch, Robin, Ignatowicz, Lech, Locke, Matthew, Lönnies, Helena, Lambris, John D., Teramura, Yuji, Nilsson-Ekdahl, Kristina, Nilsson, Bo, Le Blanc, Katarina
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4381870/
https://ncbi.nlm.nih.gov/pubmed/24805247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1729
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