Do Cryopreserved Mesenchymal Stromal Cells Display Impaired Immunomodulatory and Therapeutic Properties?

We have recently reported that therapeutic mesenchymal stromal cells (MSCs) have low engraftment and trigger the instant blood mediated inflammatory reaction (IBMIR) after systemic delivery to patients, resulting in compromised cell function. In order to optimize the product, we compared the immunom...

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Detalhes bibliográficos
Publicado no:Stem Cells
Main Authors: Moll, Guido, Alm, Jessica J., Davies, Lindsay C., von Bahr, Lena, Heldring, Nina, Stenbeck-Funke, Lillemor, Hamad, Osama A., Hinsch, Robin, Ignatowicz, Lech, Locke, Matthew, Lönnies, Helena, Lambris, John D., Teramura, Yuji, Nilsson-Ekdahl, Kristina, Nilsson, Bo, Le Blanc, Katarina
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4381870/
https://ncbi.nlm.nih.gov/pubmed/24805247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1729
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