Evidence of non-pancreatic beta cell-dependent roles of Tcf7l2 in the regulation of glucose metabolism in mice

Non-coding variation within TCF7L2 remains the strongest genetic determinant of type 2 diabetes risk in humans. A considerable effort has been placed in understanding the functional roles of TCF7L2 in pancreatic beta cells, despite evidence of TCF7L2 expression in various peripheral tissues importan...

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Опубликовано в: :Hum Mol Genet
Главные авторы: Bailey, Kathleen A., Savic, Daniel, Zielinski, Mark, Park, Soo-Young, Wang, Ling-jia, Witkowski, Piotr, Brady, Matthew, Hara, Manami, Bell, Graeme I., Nobrega, Marcelo A.
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2015
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Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4381752/
https://ncbi.nlm.nih.gov/pubmed/25398947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu577
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