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Exo-Selective Reductive Macrocyclization of Ynals
[Image: see text] A general protocol for the highly exo-selective macrocyclization of ynals using a nickel/N-heterocyclic carbene catalyst system has been developed. A series of 10- to 21-membered macrocycles bearing an exomethylene substituent was synthesized in good yields with excellent regiosele...
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| Publicado no: | Org Lett |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4381747/ https://ncbi.nlm.nih.gov/pubmed/25746060 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.5b00381 |
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