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NHC Ligands Tailored for Simultaneous Regio- and Enantio-control in Nickel-Catalyzed Reductive Couplings

An exceptionally hindered class of enantiopure NHC ligands has been developed. While racemic forms had previously been utilized, a scalable and practical route to the enantiopure form of this ligand class is described utilizing a two-directional Buchwald-Hartwig amination in a highly sterically dema...

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Detalles Bibliográficos
Publicado en:J Am Chem Soc
Autores principales: Wang, Hengbin, Lu, Gang, Sormunen, Grant J., Malik, Hasnain A., Liu, Peng, Montgomery, John
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5624313/
https://ncbi.nlm.nih.gov/pubmed/28621131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b04583
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