Posttranslational modifications in microcin B17 define an additional class of DNA gyrase inhibitor.

Drugs that inhibit the activity of DNA gyrase fall almost exclusively into two structural classes, the quinolones and the coumarins. A third class of DNA gyrase inhibitor is defined by the ribosomally synthesized peptide antibiotic microcin B17 (MccB17). MccB17 contains 43 amino acid residues, but 1...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Yorgey, P, Lee, J, Kördel, J, Vivas, E, Warner, P, Jebaratnam, D, Kolter, R
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1994
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43817/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8183941/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.10.4519
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