Lack of evidence for association of Parkin promoter polymorphism (PRKN-258) with increased risk of Parkinson's disease

Parkin (PRKN) mutations are a common cause of early-onset parkinsonism, however the role of this gene in typical late-onset Parkinson's disease (PD) remains unresolved. A single nucleotide polymorphism in the promoter region (PRKN -258; rs9347683) has been observed to associate with PD, affect...

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Veröffentlicht in:Parkinsonism Relat Disord
Hauptverfasser: Ross, Owen A., Haugarvoll, Kristoffer, Stone, Jeremy T., Heckman, Michael G., White, Linda R., Aasly, Jan O., Gibson, J. Mark, Lynch, Timothy, Wszolek, Zbigniew K., Uitti, Ryan J., Farrer, Matthew J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4381345/
https://ncbi.nlm.nih.gov/pubmed/17400506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.parkreldis.2007.01.010
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