Lack of evidence for association of Parkin promoter polymorphism (PRKN-258) with increased risk of Parkinson's disease

Parkin (PRKN) mutations are a common cause of early-onset parkinsonism, however the role of this gene in typical late-onset Parkinson's disease (PD) remains unresolved. A single nucleotide polymorphism in the promoter region (PRKN -258; rs9347683) has been observed to associate with PD, affect...

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Pubblicato in:Parkinsonism Relat Disord
Autori principali: Ross, Owen A., Haugarvoll, Kristoffer, Stone, Jeremy T., Heckman, Michael G., White, Linda R., Aasly, Jan O., Gibson, J. Mark, Lynch, Timothy, Wszolek, Zbigniew K., Uitti, Ryan J., Farrer, Matthew J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4381345/
https://ncbi.nlm.nih.gov/pubmed/17400506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.parkreldis.2007.01.010
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