Lack of evidence for association of Parkin promoter polymorphism (PRKN-258) with increased risk of Parkinson's disease

Parkin (PRKN) mutations are a common cause of early-onset parkinsonism, however the role of this gene in typical late-onset Parkinson's disease (PD) remains unresolved. A single nucleotide polymorphism in the promoter region (PRKN -258; rs9347683) has been observed to associate with PD, affect...

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Detalhes bibliográficos
Publicado no:Parkinsonism Relat Disord
Main Authors: Ross, Owen A., Haugarvoll, Kristoffer, Stone, Jeremy T., Heckman, Michael G., White, Linda R., Aasly, Jan O., Gibson, J. Mark, Lynch, Timothy, Wszolek, Zbigniew K., Uitti, Ryan J., Farrer, Matthew J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4381345/
https://ncbi.nlm.nih.gov/pubmed/17400506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.parkreldis.2007.01.010
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