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Calcium regulates processing of the Alzheimer amyloid protein precursor in a protein kinase C-independent manner.

Various first messengers linked to phospholipase C, including acetylcholine and interleukin 1, regulate the production both of the secreted form of the amyloid protein precursor (APP) and of amyloid beta-protein. We have now identified intracellular signals which are responsible for mediating these...

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Dettagli Bibliografici
Autori principali: Buxbaum, J D, Ruefli, A A, Parker, C A, Cypess, A M, Greengard, P
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1994
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC43811/
https://ncbi.nlm.nih.gov/pubmed/8183935
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