Design and characterization of ebolavirus GP prehairpin intermediate mimics as drug targets

Ebolaviruses are highly lethal filoviruses that cause hemorrhagic fever in humans and nonhuman primates. With no approved treatments or preventatives, the development of an anti-ebolavirus therapy to protect against natural infections and potential weaponization is an urgent global health need. Here...

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Detalhes bibliográficos
Publicado no:Protein Sci
Main Authors: Clinton, Tracy R, Weinstock, Matthew T, Jacobsen, Michael T, Szabo-Fresnais, Nicolas, Pandya, Maya J, Whitby, Frank G, Herbert, Andrew S, Prugar, Laura I, McKinnon, Rena, Hill, Christopher P, Welch, Brett D, Dye, John M, Eckert, Debra M, Kay, Michael S
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4380977/
https://ncbi.nlm.nih.gov/pubmed/25287718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2578
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