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The Necessity of Having a Tetradentate Ligand to Extract Copper(II) Ions from Amyloids

The accumulation of redox-active metal ions, in particular copper, in amyloid plaques is considered to the cause of the intensive oxidation damage to the brain of patients with Alzheimers disease (AD). Drug candidates based on a bis(8-aminoquinoline) tetradentate ligand are able to efficiently extra...

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Detaylı Bibliyografya
Yayımlandı:ChemistryOpen
Asıl Yazarlar: Nguyen, Michel, Rechignat, Lionel, Robert, Anne, Meunier, Bernard
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BlackWell Publishing Ltd 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4380950/
https://ncbi.nlm.nih.gov/pubmed/25861567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/open.201402075
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