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The Necessity of Having a Tetradentate Ligand to Extract Copper(II) Ions from Amyloids
The accumulation of redox-active metal ions, in particular copper, in amyloid plaques is considered to the cause of the intensive oxidation damage to the brain of patients with Alzheimers disease (AD). Drug candidates based on a bis(8-aminoquinoline) tetradentate ligand are able to efficiently extra...
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| Veröffentlicht in: | ChemistryOpen |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BlackWell Publishing Ltd
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4380950/ https://ncbi.nlm.nih.gov/pubmed/25861567 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/open.201402075 |
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