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Structural insights into selective agonist actions of tamoxifen on human Estrogen Receptor alpha
Tamoxifen, an anti-estrogenic ligand in breast tissues and being used as a first-line treatment in ER-positive breast cancers, is found to develop resistance followed by resumption of growth of the tumor in about 30% of cases. Whether tamoxifen starts assisting in proliferation in such cases or ther...
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| Опубликовано в: : | J Mol Model |
|---|---|
| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4379705/ https://ncbi.nlm.nih.gov/pubmed/25060147 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00894-014-2338-x |
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