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Insight into Estrogen Receptor Beta-Beta and Alpha-Beta Homo and Heterodimerization: A Combined Molecular Dynamics and Sequence Analysis Study
Biological effects of estrogenic ligands are transduced by two estrogen receptors, ERα and ERβ; they transactivate as dimers. Since ERββ and ERαβ homo and hetero dimers are known to exhibit anti-proliferative effects, we characterized their dimerization interface in atomic details and explored their...
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| Asıl Yazarlar: | , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2012
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4127405/ https://ncbi.nlm.nih.gov/pubmed/23085454 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpc.2012.09.002 |
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