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Ovarian insufficiency and early pregnancy loss induced by activation of the innate immune system
We describe a murine model of early pregnancy failure induced by systemic activation of the CD40 immune costimulatory pathway. Although fetal loss involved an NK cell intermediate, it was not due to lymphocyte-mediated destruction of the fetus and placenta. Rather, pregnancy failure resulted from im...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Clinical Investigation
2004
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC437968/ https://ncbi.nlm.nih.gov/pubmed/15232610 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200420645 |
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