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Pooled Sequencing and Rare Variant Association Tests for Identifying the Determinants of Emerging Drug Resistance in Malaria Parasites

We explored the potential of pooled sequencing to swiftly and economically identify selective sweeps due to emerging artemisinin (ART) resistance in a South-East Asian malaria parasite population. ART resistance is defined by slow parasite clearance from the blood of ART-treated patients and mutatio...

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Detalhes bibliográficos
Publicado no:Mol Biol Evol
Main Authors: Cheeseman, Ian H., McDew-White, Marina, Phyo, Aung Pyae, Sriprawat, Kanlaya, Nosten, François, Anderson, Timothy J.C.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4379400/
https://ncbi.nlm.nih.gov/pubmed/25534029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msu397
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