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Lower Mutation Frequency of BCP/Precore Regions in e Antigen-Negative Chronic HBV-Infected Children instead of Adults Patients

To describe the Hepatitis B e antigen(HBeAg) seroconversion related mutation profiles of the basal core promoter(BCP)/precore regions in e antigen seroconverted child patients, a cohort of 245 child patients with CHB and a control patients group of 92 adult patients with CHB were recruited. The muta...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Huang, Yong, Deng, Haijun, Shan, Xuefeng, Gong, Xuyang, Li, Xiaosong, Tu, Zen, Long, Quanxin, Huang, Ailong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4379138/
https://ncbi.nlm.nih.gov/pubmed/25822176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120733
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