HBV subgenotypes F1b and F4 replication induces an incomplete autophagic process in hepatocytes: Role of BCP and preCore mutations

Hepatitis B virus (HBV) genotypes and mutants have been associated with differences in clinical and virological characteristics. Autophagy is a cellular process that degrades long-lived proteins and damaged organelles. Viruses have evolved mechanisms to alter this process to survive in host cells. I...

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Vydáno v:PLoS One
Hlavní autoři: Elizalde, María Mercedes, Pérez, Paula Soledad, Sevic, Ina, Grasso, Daniel, Ropolo, Alejandro, Barbini, Luciana, Campos, Rodolfo Héctor, Vaccaro, María Inés, Flichman, Diego Martín
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2018
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5940199/
https://ncbi.nlm.nih.gov/pubmed/29738548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0197109
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