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Deep Sequencing Analysis of HBV Genotype Shift and Correlation with Antiviral Efficiency during Adefovir Dipivoxil Therapy
BACKGROUND: Viral genotype shift in chronic hepatitis B (CHB) patients during antiviral therapy has been reported, but the underlying mechanism remains elusive. METHODS: 38 CHB patients treated with ADV for one year were selected for studying genotype shift by both deep sequencing and Sanger sequenc...
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| izdano v: | PLoS One |
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| Main Authors: | , , , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Public Library of Science
2015
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4482366/ https://ncbi.nlm.nih.gov/pubmed/26110616 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0131337 |
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