Deep Sequencing Analysis of HBV Genotype Shift and Correlation with Antiviral Efficiency during Adefovir Dipivoxil Therapy

BACKGROUND: Viral genotype shift in chronic hepatitis B (CHB) patients during antiviral therapy has been reported, but the underlying mechanism remains elusive. METHODS: 38 CHB patients treated with ADV for one year were selected for studying genotype shift by both deep sequencing and Sanger sequenc...

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Bibliographic Details
Published in:PLoS One
Main Authors: Wang, Yuwei, Shan, Xuefeng, Liang, Zhi, Shan, Youlan, Huang, Wenxiang, Zhang, Dazhi, Zen, Aizhong, Zhou, Xin, Zhao, Yao, Gong, Xuyang, Xu, Ge, Zhang, Xiuyu, Chen, Juan, Huang, Ailong
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4482366/
https://ncbi.nlm.nih.gov/pubmed/26110616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0131337
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