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Vinpocetine Reduces Carrageenan-Induced Inflammatory Hyperalgesia in Mice by Inhibiting Oxidative Stress, Cytokine Production and NF-κB Activation in the Paw and Spinal Cord

Vinpocetine is a safe nootropic agent used for neurological and cerebrovascular diseases. The anti-inflammatory activity of vinpocetine has been shown in cell based assays and animal models, leading to suggestions as to its utility in analgesia. However, the mechanisms regarding its efficacy in infl...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Ruiz-Miyazawa, Kenji W., Zarpelon, Ana C., Pinho-Ribeiro, Felipe A., Pavão-de-Souza, Gabriela F., Casagrande, Rubia, Verri, Waldiceu A.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4379066/
https://ncbi.nlm.nih.gov/pubmed/25822523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0118942
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