Toll-like Receptor 4 Mediates the Inflammatory Responses and Matrix Protein Remodeling in Remote Non-Ischemic Myocardium in a Mouse Model of Myocardial Ischemia and Reperfusion

The signaling mechanism that mediates inflammatory responses in remote non-ischemic myocardium following regional ischemia/reperfusion (I/R) remains incompletely understood. Myocardial Toll-like receptor 4 (TLR4) can be activated by multiple proteins released from injured cells and plays a role in m...

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Pubblicato in:PLoS One
Autori principali: Zhai, Yufeng, Ao, Lihua, Cleveland, Joseph C., Zeng, Qingchun, Reece, T. Brett, Fullerton, David A., Meng, Xianzhong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4378913/
https://ncbi.nlm.nih.gov/pubmed/25823011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0121853
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