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Attenuated Recovery of Contractile Function in Aging Hearts Following Global Ischemia/Reperfusion: Role of Extracellular HSP27 and TLR4

While cardiac functional recovery is attenuated in the elderly following cardiac surgery with obligatory global myocardial ischemia/reperfusion (I/R), the underlying mechanism remains incompletely understood. We observed previously that human and mouse myocardium releases heat shock protein (HSP) 27...

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Bibliografiske detaljer
Udgivet i:Mol Med
Main Authors: Ao, Lihua, Zhai, Yufeng, Jin, Chunhua, Cleveland, Joseph C, Fullerton, David A, Meng, Xianzhong
Format: Artigo
Sprog:Inglês
Udgivet: Feinstein Institute for Medical Research 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5263054/
https://ncbi.nlm.nih.gov/pubmed/28079228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2016.00204
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