Role of intracellular tyrosines in activating KIT induced myeloproliferative disease

Gain-of-function mutations in KIT receptor in humans are associated with gastrointestinal stromal tumors (GIST), systemic mastocytosis (SM), and acute myelogenous leukemia (AML). The intracellular signals that contribute to oncogenic KIT induced myeloproliferative disease (MPD) are poorly understood...

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Vydáno v:Leukemia
Hlavní autoři: Ma, Peilin, Mali, Raghuveer Singh, Martin, Holly, Ramdas, Baskar, Sims, Emily, Kapur, Reuben
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4378686/
https://ncbi.nlm.nih.gov/pubmed/22297723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2012.22
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