Role of intracellular tyrosines in activating KIT induced myeloproliferative disease

Gain-of-function mutations in KIT receptor in humans are associated with gastrointestinal stromal tumors (GIST), systemic mastocytosis (SM), and acute myelogenous leukemia (AML). The intracellular signals that contribute to oncogenic KIT induced myeloproliferative disease (MPD) are poorly understood...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Leukemia
Egile Nagusiak: Ma, Peilin, Mali, Raghuveer Singh, Martin, Holly, Ramdas, Baskar, Sims, Emily, Kapur, Reuben
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4378686/
https://ncbi.nlm.nih.gov/pubmed/22297723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2012.22
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