Sequencing methods and datasets to improve functional interpretation of sleeping beauty mutagenesis screens

BACKGROUND: Animal models of cancer are useful to generate complementary datasets for comparison to human tumor data. Insertional mutagenesis screens, such as those utilizing the Sleeping Beauty (SB) transposon system, provide a model that recapitulates the spontaneous development and progression of...

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Udgivet i:BMC Genomics
Main Authors: Riordan, Jesse D, Drury, Luke J, Smith, Ryan P, Brett, Benjamin T, Rogers, Laura M, Scheetz, Todd E, Dupuy, Adam J
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Methodology Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4378557/
https://ncbi.nlm.nih.gov/pubmed/25526783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-1150
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