Nalaganje...

Complement protein C1q bound to apoptotic cells suppresses human macrophage and dendritic cell-mediated Th17 and Th1 T cell subset proliferation

A complete genetic deficiency of the complement protein C1q results in SLE with nearly 100% penetrance in humans, but the molecular mechanisms responsible for this association have not yet been fully determined. C1q opsonizes ACs for enhanced ingestion by phagocytes, such as Mϕ and iDCs, avoiding th...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:J Leukoc Biol
Main Authors: Clarke, Elizabeth V., Weist, Brian M., Walsh, Craig M., Tenner, Andrea J.
Format: Artigo
Jezik:Inglês
Izdano: Society for Leukocyte Biology 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4377823/
https://ncbi.nlm.nih.gov/pubmed/25381385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.3A0614-278R
Oznake: Označite
Brez oznak, prvi označite!