Dendritic cell-derived thrombospondin-1 is critical for the generation of the ocular surface Th17 response to desiccating stress

TSP-1 is a physiologic activator of TGF-β, a critical induction factor for Th17-mediated immunity. The purpose of this study was to investigate the role of TSP-1 in the induction of the Th17 ocular surface response to DS. TSP-1KO and WT mice were subjected to DS5 and DS10), and parameters of ocular...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Gandhi, Niral B., Su, Zhitao, Zhang, Xiaobo, Volpe, Eugene A., Pelegrino, Flavia S. A., Rahman, Salman A., Li, De-Quan, Pflugfelder, Stephen C., de Paiva, Cintia S.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Leukocyte Biology 2013
Assuntos:
Inflammation, Extracellular Mediators, & Effector Molecules
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4051277/
https://ncbi.nlm.nih.gov/pubmed/23983225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.1012524
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados