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Zwitterionic Poly(carboxybetaine)-based Cationic Liposomes for Effective Delivery of Small Interfering RNA Therapeutics without Accelerated Blood Clearance Phenomenon

For efficient delivery of small interfering RNA (siRNA) to the target diseased site in vivo, it is important to design suitable vehicles to control the blood circulation of siRNA. It has been shown that surface modification of cationic liposome/siRNA complexes (lipoplexes) with polyethylene glycol (...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Li, Yan, Liu, Ruiyuan, Shi, Yuanjie, Zhang, Zhenzhong, Zhang, Xin
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4377727/
https://ncbi.nlm.nih.gov/pubmed/25825598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.11234
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