Zwitterionic poly-carboxybetaine coating reduces artificial lung thrombosis in sheep and rabbits

Current artificial lungs fail in 1–4 weeks due to surface-induced thrombosis. Biomaterial coatings may be applied to anticoagulate artificial surfaces, but none have shown marked long-term effectiveness. Poly-carboxybetaine (pCB) coatings have shown promising results in reducing protein and platelet...

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Detalhes bibliográficos
Publicado no:Acta Biomater
Main Authors: Ukita, Rei, Carleton, Neil M., Naito, Noritsugu, Lai, Angela, Do-Nguyen, Chi Chi, Demarest, Caitlin T., Cook, Keith E., Wu, Kan, Lin, Xiaojie, Jiang, Shaoyi
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6633914/
https://ncbi.nlm.nih.gov/pubmed/31082571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2019.05.019
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