Ras induces experimental lung metastasis through up-regulation of RbAp46 to suppress RECK promoter activity

BACKGROUND: Mutant Ras plays multiple functions in tumorigenesis including tumor formation and metastasis. Reversion-inducing cysteine-rich protein with Kazal motifs (RECK), a metastasis inhibitor gene, suppresses matrix metalloproteinase (MMP) activity in the metastatic cascade. Clarifying the rela...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Yeh, Hsuan-Heng, Tseng, Yu-Fen, Hsu, Yu-Chiao, Lan, Sheng-Hui, Wu, Shan-Ying, Raghavaraju, Giri, Cheng, Da-En, Lee, Ying-Ray, Chang, Tsuey-Yu, Chow, Nan-Haw, Hung, Wen-Chun, Liu, Hsiao-Sheng
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4377201/
https://ncbi.nlm.nih.gov/pubmed/25885317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1155-7
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