Helicobacter hepaticus infection in BALB/c mice abolishes subunit-vaccine-induced protection against M. tuberculosis

BCG, the only licensed vaccine against tuberculosis (TB), provides geographically variable protection, an effect ascribed to exposure to environmental mycobacteria (EM). Here we show that altering the intestinal microbiota of mice by early-life infection with the commensal bacterium Helicobacter hep...

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Enregistré dans:
Détails bibliographiques
Publié dans:Vaccine
Auteurs principaux: Arnold, Isabelle C., Hutchings, Claire, Kondova, Ivanela, Hey, Ariann, Powrie, Fiona, Beverley, Peter, Tchilian, Elma
Format: Artigo
Langue:Inglês
Publié: Elsevier Science 2015
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4377097/
https://ncbi.nlm.nih.gov/pubmed/25748336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2015.02.041
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