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Helicobacter hepaticus infection in BALB/c mice abolishes subunit-vaccine-induced protection against M. tuberculosis

BCG, the only licensed vaccine against tuberculosis (TB), provides geographically variable protection, an effect ascribed to exposure to environmental mycobacteria (EM). Here we show that altering the intestinal microbiota of mice by early-life infection with the commensal bacterium Helicobacter hep...

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Detalhes bibliográficos
Publicado no:Vaccine
Main Authors: Arnold, Isabelle C., Hutchings, Claire, Kondova, Ivanela, Hey, Ariann, Powrie, Fiona, Beverley, Peter, Tchilian, Elma
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4377097/
https://ncbi.nlm.nih.gov/pubmed/25748336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2015.02.041
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