Immunization with different formulations of Mycobacterium tuberculosis antigen 85A induces immune responses with different specificity and protective efficacy()

To test the relative efficacy of CD4 and CD8T cells in mediating protective immunity to Mycobacterium tuberculosis (Mtb), we compared three immunization regimes designed to induce preferentially each subset. BALB/c mice were immunized intranasally (i.n.) or parenterally with antigen 85A either in a...

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Detalhes bibliográficos
Main Authors: Tchilian, Elma, Ahuja, Diksha, Hey, Ariann, Jiang, Shisong, Beverley, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Science 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3898716/
https://ncbi.nlm.nih.gov/pubmed/23896422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2013.07.040
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