Mismatch Repair-Deficient Crypt Foci in Lynch Syndrome – Molecular Alterations and Association with Clinical Parameters

Lynch syndrome is caused by germline mutations of DNA mismatch repair (MMR) genes, most frequently MLH1 and MSH2. Recently, MMR-deficient crypt foci (MMR-DCF) have been identified as a novel lesion which occurs at high frequency in the intestinal mucosa from Lynch syndrome mutation carriers, but ver...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:PLoS One
Päätekijät: Staffa, Laura, Echterdiek, Fabian, Nelius, Nina, Benner, Axel, Werft, Wiebke, Lahrmann, Bernd, Grabe, Niels, Schneider, Martin, Tariverdian, Mirjam, von Knebel Doeberitz, Magnus, Bläker, Hendrik, Kloor, Matthias
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2015
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4376900/
https://ncbi.nlm.nih.gov/pubmed/25816162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0121980
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia