Eicosapentaenoic Acid Ameliorates Non-Alcoholic Steatohepatitis in a Novel Mouse Model Using Melanocortin 4 Receptor-Deficient Mice

Many attempts have been made to find novel therapeutic strategies for non-alcoholic steatohepatitis (NASH), while their clinical efficacy is unclear. We have recently reported a novel rodent model of NASH using melanocortin 4 receptor-deficient (MC4R-KO) mice, which exhibit the sequence of events th...

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Udgivet i:PLoS One
Main Authors: Konuma, Kuniha, Itoh, Michiko, Suganami, Takayoshi, Kanai, Sayaka, Nakagawa, Nobutaka, Sakai, Takeru, Kawano, Hiroyuki, Hara, Mitsuko, Kojima, Soichi, Izumi, Yuichi, Ogawa, Yoshihiro
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4376873/
https://ncbi.nlm.nih.gov/pubmed/25816330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0121528
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