Lung Fibroblasts Share Mesenchymal Stem Cell Features Which Are Altered in Chronic Obstructive Pulmonary Disease via the Overactivation of the Hedgehog Signaling Pathway

BACKGROUND: Alteration of functional regenerative properties of parenchymal lung fibroblasts is widely proposed as a pathogenic mechanism for chronic obstructive pulmonary disease (COPD). However, what these functions are and how they are impaired in COPD remain poorly understood. Apart from the rol...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Figeac, Florence, Dagouassat, Maylis, Mahrouf-Yorgov, Meriem, Le Gouvello, Sabine, Trébeau, Céline, Sayed, Angeliqua, Stern, Jean-Baptiste, Validire, Pierre, Dubois-Randé, Jean-Luc, Boczkowski, Jorge, Mus-Veteau, Isabelle, Rodriguez, Anne-Marie
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4376723/
https://ncbi.nlm.nih.gov/pubmed/25815884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0121579
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