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Overactivation of Hedgehog Signaling in the Developing Müllerian Duct Interferes with Duct Regression in Males and Causes Subfertility

The influence of the hedgehog signaling pathway on reproduction was studied in transgenic mice in which a dominant active allele of the hedgehog signal transducer, smoothened (SMOM2), was conditionally expressed in the developing Müllerian duct and gonads through recombination mediated by anti-Mülle...

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Detalhes bibliográficos
Publicado no:Reproduction
Main Authors: Migone, Fernando F., Hung, Pei-hsuan, Cowan, Robert G., Selvaraj, Vimal, Suarez, Susan S., Quirk, Susan M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5328643/
https://ncbi.nlm.nih.gov/pubmed/28123059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/REP-16-0562
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