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Overactivation of Hedgehog Signaling in the Developing Müllerian Duct Interferes with Duct Regression in Males and Causes Subfertility

The influence of the hedgehog signaling pathway on reproduction was studied in transgenic mice in which a dominant active allele of the hedgehog signal transducer, smoothened (SMOM2), was conditionally expressed in the developing Müllerian duct and gonads through recombination mediated by anti-Mülle...

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Détails bibliographiques
Publié dans:Reproduction
Auteurs principaux: Migone, Fernando F., Hung, Pei-hsuan, Cowan, Robert G., Selvaraj, Vimal, Suarez, Susan S., Quirk, Susan M.
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5328643/
https://ncbi.nlm.nih.gov/pubmed/28123059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/REP-16-0562
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