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Overactivation of Hedgehog Signaling in the Developing Müllerian Duct Interferes with Duct Regression in Males and Causes Subfertility

The influence of the hedgehog signaling pathway on reproduction was studied in transgenic mice in which a dominant active allele of the hedgehog signal transducer, smoothened (SMOM2), was conditionally expressed in the developing Müllerian duct and gonads through recombination mediated by anti-Mülle...

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Bibliografske podrobnosti
izdano v:Reproduction
Main Authors: Migone, Fernando F., Hung, Pei-hsuan, Cowan, Robert G., Selvaraj, Vimal, Suarez, Susan S., Quirk, Susan M.
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5328643/
https://ncbi.nlm.nih.gov/pubmed/28123059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/REP-16-0562
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