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Overactivation of Hedgehog Signaling Alters Development of the Ovarian Vasculature in Mice

The hedgehog (HH) signaling pathway is critical for ovarian function in Drosophila, but its role in the mammalian ovary has not been defined. Previously, expression of a dominant active allele of the HH signal transducer protein smoothened (SMO) in Amhr2(cre/+)SmoM2 mice caused anovulation in associ...

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Библиографические подробности
Главные авторы: Ren, Yi, Cowan, Robert G., Migone, Fernando F., Quirk, Susan M.
Формат: Artigo
Язык:Inglês
Опубликовано: Society for the Study of Reproduction, Inc. 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3386146/
https://ncbi.nlm.nih.gov/pubmed/22402963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.112.099176
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