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Overactivation of Hedgehog Signaling Alters Development of the Ovarian Vasculature in Mice

The hedgehog (HH) signaling pathway is critical for ovarian function in Drosophila, but its role in the mammalian ovary has not been defined. Previously, expression of a dominant active allele of the HH signal transducer protein smoothened (SMO) in Amhr2(cre/+)SmoM2 mice caused anovulation in associ...

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Hlavní autoři: Ren, Yi, Cowan, Robert G., Migone, Fernando F., Quirk, Susan M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for the Study of Reproduction, Inc. 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3386146/
https://ncbi.nlm.nih.gov/pubmed/22402963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.112.099176
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